In our daily life, the importance of heterocyclic compounds is very essential. It has a broad range of applications in medicinal chemistry. Benzotriazole is a bicyclic heterocyclic system consisting of three nitrogen atoms and a fused benzene ring, shows wide range of biological and pharmacologica Micro sponges are patented polymeric drug delivery systems consisting of porous microspheres.
The physical appearance of microsponges is tiny spherical sponge-like with the surface with large spores. Micro sponges are typically used and nowadays used as the oral dosage form.
The inert and indestructible tiny spherical particles do not pass through the skin. But, it collects in the tiny nooks and c Patients and Methods: We made this study on subjects men divided into four groups 30 healthy control Seaweeds are potential sources of bioactive molecules. They are known to be rich sources of proteins, carbohydrates, lipids, vitamins, minerals, and other secondary metabolites.
To evaluate the presence of these compounds in marine macroalgae collected from Veraval coast of Gujarat, present studies was carried out. The methanol extract of six macroalgae species Ulva lactuca, Ulva faciata, Acantho Topical formulations may contribute to the reduction of oxidative stress in the skin.
Banana peel is a fruit waste with antioxidant activity that is not yet included in a topical formulation. The aim of this study was to evaluate the antioxidant and anti-aging activity of a cream formulation containing a lyophilized extract of banana peel.
The banana peel was extracted with ethanol, and a cream fo A new series of Schiff's base compounds were synthesized by condensation of 1- 4-amino-4 phenyl 3-phenyl triazeneol and substituted aldehyde and gave high yields of target compounds. Antimicrobial activity of compounds has been tested against bacterial and fungal species, namely gram-positive bacteria as S.
The antibacterial property of three Himalayan Oaks species Quercus floribunda, Q. It is an open access online and print International Journal published monthly. It also represents the core structure of several molecules of pharmaceutical importance. Interest in synthesizing some coumarin derivatives with the aim of testing their microbiological activity.
Synthesis All reactions were carried out under dry and deoxygenated argon Atmosphere. Solvents were used as anhydrous by reflux of each solvent over an appropriate dryer agent and further distillate under argon atmosphere. And a few drops of piperidine were mixed for 5 minutes at room temperature without any solvent. Reaction was neutralized with HCl 1M and finally the product was isolated by filtration.
The final compound was then recrystallized in EtOH. Reaction: DOI: Mixture was cooled and the resulting solid was filtered and purified by recrystallization.
Purification of compounds was made by recrystallization in MeOH. DOI: Name of the Product Practical yield M. It was prepared by refluxing 3-acetyl Coumarin and Benzaldehyde in presence of piperidine using Ethanol as a solvent. Was also synthesized by refluxing 3-acetyl Coumarin a Anisaldehyde in presence of piperidin as a base.
Conclusion: In this study, we synthesized various substituted Coumarins and they were converted to Coumarin- Chalcone hybrids. We have confirmed the considerable antioxidant activity of new hydroxylated coumarin-chalcone hybrid compounds. Their antioxidant activity is affected by the introduction of a benzoyl moiety at the C3 position regarding to the coumarin ring. A very interesting finding is that compounds are very reactive and presents good antioxidant capacity against hydroxyl radicals as well as low oxidation potential.
In spite of the moderate trypanocidal activity of coumarin-chalcone hybrids, they have been proved to be very good antioxidants. Based on these results, we can conclude that compounds are potential candidates for the studies of their antioxidant activity. Ukhov, S. Synthesis and antimicrobial activity of 2-iminocoumarincorboxylic acid amides. Abd Elhafez, O. Basangouda, M.
Liu, X. Appl Microbiol Biotechnol. Trapkov, V. Related Papers. Download pdf. Log in with Facebook Log in with Google.
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